Module Code - Title:
CH4417
-
PHARMACEUTICAL FORMULATION
Year Last Offered:
2023/4
Hours Per Week:
Grading Type:
N
Prerequisite Modules:
CH4003
CH4004
CH4005
CH4405
CH4415
Rationale and Purpose of the Module:
To draw on a knowledge of basic physical chemistry and chemical unit operations in order to understand the efficient design and formulation of medicines as well as the manufacture of these medicines on both a small (compounding) and a large (pharmaceutical technology) scale.
Syllabus:
Physical Chemical principles of dosage from design
Particle science & powder technology
Biopharmaceutics
Dosage form design & manufacture
Learning Outcomes:
Cognitive (Knowledge, Understanding, Application, Analysis, Evaluation, Synthesis)
Acknowledge the importance of the physicochemical characteristics of active pharmaceutical ingredients (API) in the design and preparation of dosage forms.
Recognise how drug release and absorbtion are strongly dependent on solution properties such as solute dissolution, diffusion and flow properties.
Select appropriate additives in the formulation to control dissloution, taste, stability, rheology and increase shelf life of the product.
Explain how the internal, surface and macroscopic propertiesof paricles and powders influence their performance during the design and manufacture of dosage forms.
Predict the rate and extent of the release of drugs from dosage forms.
Propose appropriate unit operations and scheduling for dosage form design and manufacture
Affective (Attitudes and Values)
Demonstrate an appreciation of the role of scientific and engineering principles in the design, formulation and manufacture of medicines.
Psychomotor (Physical Skills)
n/a
How the Module will be Taught and what will be the Learning Experiences of the Students:
The module will be taught over a 12 week period through a formal interactive lecturing mode (2 x 1 hour lectures + 1 x1 hour tutorial). In addition students will be given group assignments.
The module will be assessed by an end-of-semester written exam (60% of final marks); 40% of the marks will be awarded for oral presentation and written reports of assignments.
Research Findings Incorporated in to the Syllabus (If Relevant):
n/a
Prime Texts:
M.E. Aulton (2002)
Pharmaceutics
, Churchill Livingstone
Loyd V. Allen, Howard C. Ansel, Nicholas G. Popovich (2004)
Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems 8e
, Lippincott Williams & Wilkins
Other Relevant Texts:
Programme(s) in which this Module is Offered:
Semester - Year to be First Offered:
Autumn
-
09/10
Module Leader:
sarah.hudson@ul.ie